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  • Original Article|Open Access

    Gene expression and carbonic anhydrase IX promoter methylation in oral cancer and smokers oral mucosa: a pilot study

    Mônica Ghislaine Oliveira Alves , Celina Faig Lima Carta , Maria-Elena Padín-Iruegas , Mario Pérez-Sayáns , Rafael López-López , Nieves Martínez Lago , José Manuel Suárez-Peñaranda , Jaqueline Scholz Issa , Abel García-García , Janete Dias Almeida
    Aim: To evaluate the methylation of carbonic anhydrase IX (CAIX) promoter and CAIX gene expression in oral cancer and smokers. Methods: The collected oral cells samples were classified in to five groups, with each group containing 15 samples. Group 1, oral squamous cell carcinoma (OSCC); group 2, normal contralateral mucosa (NCM) of patients from group OSCC; group 3, normal mucosa in chronic smokers (CS); group 4, normal mucosa in ex-smokers (ES) in cessation for one year; and group 5, normal mucosa in never-smokers (NS). Samples were evaluated through methylation-specific polymerase chain... Read more
    Published on: 13 Dec 2017  | Viewed:0  | Downloaded:0
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  • Original Article|Open Access

    Correlation between salivary cortisol levels and Hospital Anxiety and Depression scores in oral lichen planus and recurrent aphthous stomatitis

    Vaishnavee Vassandacoumara , Jonathan M. Daniel
    Aim: The aim of this study was to estimate the salivary cortisol levels in patients with oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS) and to correlate it with their psychological profile using the Hospital Anxiety and Depression (HAD) scale. Methods: The study population comprised of 60 patients - 20 with OLP, 20 with RAS and 20 healthy controls. Salivary cortisol levels were assessed using the chemiluminescent immuno assay technique. Anxiety and depression levels were evaluated using the HAD scale. Results: The Kruskal Wallis mean ranks of salivary cortisol level in the... Read more
    Published on: 28 Nov 2017  | Viewed:64  | Downloaded:4
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  • Original Article|Open Access

    Shear bond strength of universal adhesive systems to a bioactive dentin substitute (Biodentine®) at different time intervals

    Sedef Aksoy , Murat Ünal
    Aim: The aim of this study was to compare the shear bond strength (SBS) of various adhesive systems to a bioactive dentin substitute Biodentine® with different time intervals. Methods: Three hundred and fifty cylindrical acrylic blocks with a hole (4 mm diameter and 2 mm height) were prepared. The holes were filled with Biodentine®, and the specimens were allocated into 5 main groups according to waiting times (group 1, 12 min; group 2, 24 h; group 3, 48 h; group 4, 72 h; and group 5, 96 h). All specimens were stored at 37 °C with 100% humidity during the waiting time. Then each group was... Read more
    Published on: 19 Oct 2017  | Viewed:609  | Downloaded:24
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Stomatological Disease and Science Online ISSN: 2573-0002
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