Aim: The study was to correlate the survival of a group of Sri Lankan betel quid induced oral cancer patients with the expression patterns of five cancer stem cell (CSC) markers namely ALDH1, Sox-2, Bmi-1, C-met, and Oct-4. Methods: Archival tissues of 140 oral squamous cell carcinomas (OSCCs) were stained with CSC markers, ALDH1, Sox-2, Bmi-1, C-met, and Oct-4. Survival analysis was performed with SPSS version 20, using Kaplan-Meier survival curves and significance with chi-square test and Breslow’s (generalized Wilcoxon) test. Results: Immunohistochemical investigations revealed 55.7%,...
Published on: 31 Mar 2017